IMMUNOLOGY: Helpful Helminths

Masters of Immunology CD4 T-cell Subsets and Tumor Immunity: The Helpful and the Not-so-Helpful

Research over the past decade has revealed the increasingly complex biologic features of the CD4þ T-cell lineage. This T-cell subset, which was originally defined on the basis of helper activity in antibody responses, expresses receptors that recognize peptides that have been processed and presented by specialized antigenpresenting cells. At the core of the adaptive immune response, CD4 T cells...

Immunology

Immunology.

The pathological changes involved in the immunological lung diseases of the bronchiolar region are reviewed. Next, the possibility that BOOP and DPB, two diseases whose causes are presently unknown, are caused by immune responses, is discussed.

Immunology

Homing in on helminths.

I am honored to give this lecture dedicated to the memory of Dr. Fred Soper, whose pioneering efforts against the insect vectors of malaria and yellow fever are legendary. Soper and his col leagues also played key roles in restoring the con cept of eradication to respectability after the col lapse of earlier campaigns to eradicate hookworm and yellow fever. When Soper was himself in vited to gi...